| Treatment Options |
Cost |
Durabilty |
Adverse events |
Sweating areas being effected |
Treatment Intervals |
| Drug therapy(anti-depressants; psychotropics; anti-arrhythmics; glycopirolate; diazepam; Indomethacin; topical aluminium chloride
|
++ |
None |
These drugs might also increase sweating. Mouth dryness; blurry-fuzzy vision; distorted speech-taste-chewing-swallowing functions; urine retention; constipation; palpitation-throbbing; itching; severe allergic reactions
|
Hands – Face – Armpits - Feet
|
Every day (drug usage incompa-tibility is very high)
|
| Botulinum Toxin - A |
+++++
(multiple injections)
|
6 wks – 6 mos
|
Pain
Possibility for missing area injections
|
Hands – Face - Armpits
|
At least 2 times a year
|
| Iontophoresis (mild electrical current) |
+++++
number of repeat sessions is high
|
1 wk – 1 mo (requires many sessions)
|
Pain, sting, electrical shock, skin irritation, it should NOT be used in pregnants, patients with cardiac pace, hip prosthesis and epilepsy
|
Hands - Feet
|
Multiple |
ETS – (endoscopic thoracic sympathectomy)
|
Cost = 4 x botulinum appliance cost |
Durable for many years
(>12 yrs, 50-60% of the patients are still satisfied)
Quality-of-life is very high
|
Loss of sensation-1%; Infection-0.1%; Wound pain-2%; Horner syndrome-0.5%; compensatory sweating- 20-80%; 10%-reduc-tion in the heart rate in almost all patients
|
Hands – Face – Armpits - Feet
|
Very seldom
(If needed it can be done safely) |
